Exposure-response relationships in asthma caused by tetrachlorophthalic anhydride
Four patients with asthma caused by occupational exposure to tetrachlorophthalic anhydride (TCPA) had dust-challenge tests that used eight different levels ofTCPA exposure. Measurements ofTCPA in the test-cubicle air ranged from 1.3 to 961.1 fjig/m3. The higher exposures provoked definite late or du...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
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1990
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| _version_ | 1826282153175941120 |
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| author | Venables, K Taylor, A |
| author_facet | Venables, K Taylor, A |
| author_sort | Venables, K |
| collection | OXFORD |
| description | Four patients with asthma caused by occupational exposure to tetrachlorophthalic anhydride (TCPA) had dust-challenge tests that used eight different levels ofTCPA exposure. Measurements ofTCPA in the test-cubicle air ranged from 1.3 to 961.1 fjig/m3. The higher exposures provoked definite late or dual asthmatic responses. Smaller, but statistically significant, responses were observed at low exposures. The late asthmatic-response area had a linear relation to the logarithm of TCPA exposure, but the immediate asthmatic response was less closely related to exposure. |
| first_indexed | 2024-03-07T00:39:32Z |
| format | Journal article |
| id | oxford-uuid:828edc04-4608-4dec-bd36-a50788535822 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T00:39:32Z |
| publishDate | 1990 |
| record_format | dspace |
| spelling | oxford-uuid:828edc04-4608-4dec-bd36-a507885358222022-03-26T21:38:25ZExposure-response relationships in asthma caused by tetrachlorophthalic anhydrideJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:828edc04-4608-4dec-bd36-a50788535822EnglishSymplectic Elements at Oxford1990Venables, KTaylor, AFour patients with asthma caused by occupational exposure to tetrachlorophthalic anhydride (TCPA) had dust-challenge tests that used eight different levels ofTCPA exposure. Measurements ofTCPA in the test-cubicle air ranged from 1.3 to 961.1 fjig/m3. The higher exposures provoked definite late or dual asthmatic responses. Smaller, but statistically significant, responses were observed at low exposures. The late asthmatic-response area had a linear relation to the logarithm of TCPA exposure, but the immediate asthmatic response was less closely related to exposure. |
| spellingShingle | Venables, K Taylor, A Exposure-response relationships in asthma caused by tetrachlorophthalic anhydride |
| title | Exposure-response relationships in asthma caused by tetrachlorophthalic anhydride |
| title_full | Exposure-response relationships in asthma caused by tetrachlorophthalic anhydride |
| title_fullStr | Exposure-response relationships in asthma caused by tetrachlorophthalic anhydride |
| title_full_unstemmed | Exposure-response relationships in asthma caused by tetrachlorophthalic anhydride |
| title_short | Exposure-response relationships in asthma caused by tetrachlorophthalic anhydride |
| title_sort | exposure response relationships in asthma caused by tetrachlorophthalic anhydride |
| work_keys_str_mv | AT venablesk exposureresponserelationshipsinasthmacausedbytetrachlorophthalicanhydride AT taylora exposureresponserelationshipsinasthmacausedbytetrachlorophthalicanhydride |