Shigella sonnei meningitis due to interleukin-1 receptor-associated kinase-4 deficiency: first association with a primary immune deficiency.

BACKGROUND: Inherited interleukin-1-receptor-associated kinase-4 (IRAK-4) deficiency is a recently described immunodeficiency associated with pyogenic bacterial infections and a poor inflammatory response. Shigella sonnei is generally associated with outbreaks of rectocolitis in developed countries...

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Detalles Bibliográficos
Autores principales: Chapel, H, Puel, A, von Bernuth, H, Picard, C, Casanova, J
Formato: Journal article
Lenguaje:English
Publicado: 2005