Molecular interactions of nitrogen-containing bisphosphonates within farnesyl diphosphate synthase
Bisphosphonates, known for their effectiveness in the treatment of osteoporosis, inhibit bone resorption via mechanisms that involve binding to bone mineral and cellular effects on osteoclasts. The major molecular target of nitrogen-containing bisphosphonates (N-BPs) in osteoclasts is farnesyl dipho...
| Principais autores: | , , , , , , , |
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| Formato: | Conference item |
| Publicado em: |
2005
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