Nanopore sequencing and full genome de novo assembly of Human Cytomegalovirus TB40/E reveals clonal diversity and structural variations

<p>Background: Human cytomegalovirus (HCMV) has a double-stranded DNA genome of approximately 235 Kbp that is structurally complex including extended GC-rich repeated regions. Genomic recombination events are frequent in HCMV cultures but have also been observed in vivo. Thus, the assembly of...

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Bibliographic Details
Main Authors: Karamitros, T, van Wilgenburg, B, Wills, M, Klenerman, P, Magiorkinis, G
Format: Journal article
Published: BioMed Central 2018