Systemic NMDA antagonist CGP-37849 produces non-specific impairment in a working memory task: the effect does not resemble those of AP5 and of lesions of the hippocampus or fornix.
The N-methyl-D-aspartate (NMDA) receptor antagonist CGP-37849 (D,L-(E)-2-amino-4-methyl-5-phosphono-3-pentenoic acid), administered i.p. (2.0 and 4.0 mg/kg), impaired rats' performance in a delayed matching-to-sample working memory task. This task is sensitive to hippocampal/fornix lesions or i...
Príomhchruthaitheoirí: | Gutnikov, SA, Rawlins, J |
---|---|
Formáid: | Journal article |
Teanga: | English |
Foilsithe / Cruthaithe: |
1996
|
Míreanna comhchosúla
Míreanna comhchosúla
-
Effects of the competitive NMDA receptor antagonist CGP 37849 on performance of reference and working memory tasks by rats.
de réir: Deacon, R, et al.
Foilsithe / Cruthaithe: (1995) -
Systemic NMDA receptor antagonist CGP-40116 does not impair memory acquisition but protects against NMDA neurotoxicity in rhesus monkeys.
de réir: Gutnikov, SA, et al.
Foilsithe / Cruthaithe: (1996) -
Determinants of non-spatial working memory deficits in rats given intraventricular infusions of the NMDA antagonist AP5.
de réir: Lyford, G, et al.
Foilsithe / Cruthaithe: (1993) -
Critical determinants of nonspatial working memory deficits in rats with conventional lesions of the hippocampus or fornix.
de réir: Rawlins, J, et al.
Foilsithe / Cruthaithe: (1993) -
Effects of GABAB receptor antagonists CGP63360, CGP76290A and CGP76291A on learning and memory processes in rodents
de réir: Getova Damianka, et al.
Foilsithe / Cruthaithe: (2007-09-01)