Rev binds specifically to a purine loop in the SL1 region of the HIV-1 leader RNA.
The leader RNA sequence of human immunodeficiency virus type 1 (HIV-1) consists of a complex series of stem loop structures that are critical for viral replication. Three-dimensional structural analysis by NMR of one of these structures, the SL1 stem loop of the packaging signal region, revealed a h...
Main Authors: | Gallego, J, Greatorex, J, Zhang, H, Yang, B, Arunachalam, S, Fang, J, Seamons, J, Lea, S, Pomerantz, R, Lever, A |
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格式: | Journal article |
语言: | English |
出版: |
2003
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