Increased expression of surface IgM but not IgD or IgG on human B cells in response to IL-4.
Surface IgM (sIgM) was increased up to 10 times on human tonsillar B cells activated with IL-4. No change was observed for surface IgD, IgG or IgE. Other activators of human B cells, such as TPA, EBV and anti-IgM resulted in increased expression of the low-affinity receptor for IgE (CD23), but had n...
Hlavní autoři: | Shields, J, Armitage, R, Jamieson, B, Beverley, P, Callard, R |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
1989
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