T cell receptor usage of virus-specific CD8 cells and recognition of viral mutations during acute and persistent hepatitis B virus infection.

T cell receptor usage of virus-specific CD8 cells and recognition of viral mutations during acute and persistent hepatitis B virus infection.

T cells specific for a single viral epitope, but using different T cell receptors, should have flexibility in their epitope recognition to protect the infected host against the emergence of viral escape mutants. Therefore, polyclonality of the hepatitis B virus (HBV)-specific cytotoxic T lymphocyte...

Полное описание

Библиографические подробности
Главные авторы:	Maini, M, Reignat, S, Boni, C, Ogg, G, King, A, Malacarne, F, Webster, G, Bertoletti, A
Формат:	Journal article
Язык:	English
Опубликовано:	2000

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