Concise and highly selective asymmetric synthesis of acosamine from sorbic acid

Diastereoselective conjugate addition of lithium (R)-N-benzyl-N-(α- methylbenzyl)amide to tert-butyl sorbate and subsequent chemo- and diastereoselective ammonium-directed olefinic oxidation of the resultant conjugate addition product {tert-butyl (3S,αR)-3-[N-benzyl-N-(α- methylbenzyl)amino]hex-4-en...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Bagal, S, Davies, S, Fletcher, A, Lee, J, Roberts, P, Scott, P, Thomson, J
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2011