Concise and highly selective asymmetric synthesis of acosamine from sorbic acid
Diastereoselective conjugate addition of lithium (R)-N-benzyl-N-(α- methylbenzyl)amide to tert-butyl sorbate and subsequent chemo- and diastereoselective ammonium-directed olefinic oxidation of the resultant conjugate addition product {tert-butyl (3S,αR)-3-[N-benzyl-N-(α- methylbenzyl)amino]hex-4-en...
Autori principali: | , , , , , , |
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Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
2011
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