Glucocorticosteroids as dengue therapeutics: resolving clinical observations with a primary human macrophage model.
A recent trial [1] investigated the use of a glucocorticosteroid, prednisolone, as a therapy for reduction of severe dengue disease. Many pathogens induce accelerated or excessive inflammation, resulting in detrimental rather than protective effects [2], and dengue virus is a well-characterized exam...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Oxford University Press
2012
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