Stimulus-secretion coupling in pancreatic beta cells.
Insulin secretion is triggered by a rise in the intracellular Ca2+ concentration that results from the activation of voltage-gated Ca2+ channels in the beta-cell plasma membrane. Multiple types of beta-cell Ca2+ channel have been identified in both electrophysiological and molecular biological studi...
Main Authors: | Ashcroft, F, Proks, P, Smith, P, Ammälä, C, Bokvist, K, Rorsman, P |
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Format: | Journal article |
Language: | English |
Published: |
1994
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