A comprehensive genetic profile of phyllodes tumours of the breast detects important mutations, intra-tumoral genetic heterogeneity and new genetic changes on recurrence.
The aims of this study were to identify genetic changes associated with malignant progression of the fibroepithelial neoplasms, phyllodes tumours of the breast (PTs), and to ascertain whether genetic progression occurs when PTs recur locally. A further aim was to assess whether the genetic data supp...
Հիմնական հեղինակներ: | Jones, A, Mitter, R, Springall, R, Graham, T, Winter, E, Gillett, C, Hanby, A, Tomlinson, I, Sawyer, E |
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Ձևաչափ: | Journal article |
Լեզու: | English |
Հրապարակվել է: |
2008
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Նմանատիպ նյութեր
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mRNA expression profiling of phyllodes tumours of the breast: identification of genes important in the development of borderline and malignant phyllodes tumours.
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Beta-catenin abnormalities and associated insulin-like growth factor overexpression are important in phyllodes tumours and fibroadenomas of the breast.
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The Wnt pathway, epithelial-stromal interactions, and malignant progression in phyllodes tumours.
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Malignant phyllodes tumours show stromal overexpression of c-myc and c-kit.
: Sawyer, E, և այլն
Հրապարակվել է: (2003) -
Molecular analysis of phyllodes tumors reveals distinct changes in the epithelial and stromal components.
: Sawyer, E, և այլն
Հրապարակվել է: (2000)