| Summary: | <p><strong>Background:</strong> Limited information is available about patterns of surgical management of early breast cancer by ethnicity of women in England, and any potential inequalities in the treatment received for breast cancer.</p>
<p><strong>Methods:</strong> National Cancer Registration and Analysis Service (NCRAS) data for 164 143 women diagnosed with early invasive breast cancer (ICD-10 C50) during 2012-2017 was analysed. Multivariable logistic regression was used to estimate odds ratios (OR) and 95% confidence intervals (CIs) for the risk of mastectomy versus breast conserving surgery by ethnicity (Black African, Black Caribbean, Indian, Pakistani, White), adjusting for age, region, deprivation, year of diagnosis, comorbidity and stage at
diagnosis.</p>
<p><strong>Results:</strong> The proportion of women undergoing mastectomy fell by ~5% during 2012 to 2017 across all the ethnic groups examined. In unadjusted analyses, each ethnic minority group had a significantly higher odds of mastectomy compared to White women; however in the fully adjusted model, there were no significantly increased odds for mastectomy for women of any ethnic minority groups
examined. For example, compared to White women, the unadjusted and fully adjusted OR (95% confidence interval) for mastectomy was 1.14 (1.05-1.20) and 1.04 (0.96-1.14) for Indian women, and 1.45 (1.30-1.62) and 1.00 (0.89-1.13) for Black African women. This attenuation in the odds ratios by ethnicity was largely due to adjustment for age and stage.</p>
<p><strong>Conclusions:</strong> Allowing for different patterns of age and stage at presentation, the surgical management of early breast cancer is similar in all women, regardless of ethnicity.</p>
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