Dopamine spillover after quantal release: rethinking dopamine transmission in the nigrostriatal pathway.
The predominance of dopamine (DA) receptors at extrasynaptic vs. synaptic sites implies that DA signaling is by diffusion-based volume transmission. In this review, we compare characteristics that regulate extracellular DA behavior in substantia nigra pars compacta (SNc) and striatum, including regi...
Main Authors: | Rice, M, Cragg, S |
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Format: | Journal article |
Language: | English |
Published: |
2008
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