KIR3DL2 binds to HLA-B27 dimers and free H chains more strongly than other HLA class I and promotes the expansion of T cells in ankylosing spondylitis.
The human leukocyte Ag HLA-B27 (B27) is strongly associated with the spondyloarthritides. B27 can be expressed at the cell surface of APC as both classical β2-microglobulin-associated B27 and B27 free H chain forms (FHC), including disulfide-bonded H chain homodimers (termed B27(2)). B27 FHC forms,...
المؤلفون الرئيسيون: | Wong-Baeza, I, Ridley, A, Shaw, J, Hatano, H, Rysnik, O, McHugh, K, Piper, C, Brackenbridge, S, Fernandes, R, Chan, A, Bowness, P, Kollnberger, S |
---|---|
التنسيق: | Journal article |
اللغة: | English |
منشور في: |
2013
|
مواد مشابهة
-
KIR3DL2 Binds to HLA-B27 Dimers and Free H Chains More Strongly than Other HLA Class I and Promotes the Expansion of T Cells in Ankylosing Spondylitis.
حسب: Wong-Baeza, I, وآخرون
منشور في: (2013) -
KIR3DL2 INTERACTION WITH HLA-B27 PROMOTES THE SURVIVAL OF TH17 CELLS IN ANKYLOSING SPONDYLITIS
حسب: Kollnberger, S, وآخرون
منشور في: (2010) -
EXPRESSION OF HLA-B27 HEAVY CHAIN FORMS IN ANKYLOSING SPONDYLITIS AND HLA-B27 POSITIVE CELL LINES
حسب: Rysnik, O, وآخرون
منشور في: (2012) -
KIR3DL2 INTERACTION WITH HLA-B27 PROMOTES THE SURVIVAL OF TH17 CELLS IN ANKYLOSING SPONDYLITIS
حسب: Kollnberger, S, وآخرون
منشور في: (2010) -
Th17 cells expressing KIR3DL2+ and responsive to HLA-B27 homodimers are increased in ankylosing spondylitis.
حسب: Bowness, P, وآخرون
منشور في: (2011)