An analysis of substrate binding interactions in the heme peroxidase enzymes: a structural perspective.

The interactions of heme peroxidase enzymes with their substrates have been studied for many years, but only in the last decade or so has structural information begun to appear. This review looks at crystal structures for a number of heme peroxidases in complex with a number of (mainly organic) subs...

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Detalhes bibliográficos
Principais autores: Gumiero, A, Murphy, E, Metcalfe, C, Moody, P, Raven, E
Formato: Journal article
Idioma:English
Publicado em: 2010
Descrição
Resumo:The interactions of heme peroxidase enzymes with their substrates have been studied for many years, but only in the last decade or so has structural information begun to appear. This review looks at crystal structures for a number of heme peroxidases in complex with a number of (mainly organic) substrates. It examines the nature and location of the binding interaction, and explores functional similarities and differences across the family.