Loss of mutual protection between human osteoclasts and chondrocytes in damaged joints initiates osteoclast-mediated cartilage degradation by MMPs
Osteoclasts are multinucleated, bone-resorbing cells. However, they also digest cartilage during skeletal maintenance, development and in degradative conditions including osteoarthritis, rheumatoid arthritis and primary bone sarcoma. This study explores the mechanisms behind the osteoclast–cartilage...
المؤلفون الرئيسيون: | Larrouture, Q, Cribbs, A, Rao, S, Philpott, M, Snelling, S, Knowles, H |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
Springer Nature
2021
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مواد مشابهة
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Osteoclasts are multinucleated cells that degrade cartilage as well as bone
حسب: Larrouture, Q, وآخرون
منشور في: (2018) -
Osteoclasts are multinucleated cells that degrade cartilage as well as bone
حسب: Larrouture, QC
منشور في: (2019) -
Osteoclasts degrade bone and cartilage knee joint compartments through different resorption processes
حسب: Henrik Löfvall, وآخرون
منشور في: (2018-04-01) -
Osteoclast-associated receptor blockade prevents articular cartilage destruction via chondrocyte apoptosis regulation
حسب: Doo Ri Park, وآخرون
منشور في: (2020-08-01) -
Chondroclasts are mature osteoclasts which are capable of cartilage matrix resorption
حسب: Knowles, H, وآخرون
منشور في: (2012)