Loss of mutual protection between human osteoclasts and chondrocytes in damaged joints initiates osteoclast-mediated cartilage degradation by MMPs
Osteoclasts are multinucleated, bone-resorbing cells. However, they also digest cartilage during skeletal maintenance, development and in degradative conditions including osteoarthritis, rheumatoid arthritis and primary bone sarcoma. This study explores the mechanisms behind the osteoclast–cartilage...
主要な著者: | Larrouture, Q, Cribbs, A, Rao, S, Philpott, M, Snelling, S, Knowles, H |
---|---|
フォーマット: | Journal article |
言語: | English |
出版事項: |
Springer Nature
2021
|
類似資料
-
Osteoclasts are multinucleated cells that degrade cartilage as well as bone
著者:: Larrouture, Q, 等
出版事項: (2018) -
Osteoclasts are multinucleated cells that degrade cartilage as well as bone
著者:: Larrouture, QC
出版事項: (2019) -
Osteoclasts degrade bone and cartilage knee joint compartments through different resorption processes
著者:: Henrik Löfvall, 等
出版事項: (2018-04-01) -
Osteoclast-associated receptor blockade prevents articular cartilage destruction via chondrocyte apoptosis regulation
著者:: Doo Ri Park, 等
出版事項: (2020-08-01) -
Chondroclasts are mature osteoclasts which are capable of cartilage matrix resorption
著者:: Knowles, H, 等
出版事項: (2012)