Loss of mutual protection between human osteoclasts and chondrocytes in damaged joints initiates osteoclast-mediated cartilage degradation by MMPs

Loss of mutual protection between human osteoclasts and chondrocytes in damaged joints initiates osteoclast-mediated cartilage degradation by MMPs

Osteoclasts are multinucleated, bone-resorbing cells. However, they also digest cartilage during skeletal maintenance, development and in degradative conditions including osteoarthritis, rheumatoid arthritis and primary bone sarcoma. This study explores the mechanisms behind the osteoclast–cartilage...

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Bibliografische gegevens
Hoofdauteurs:	Larrouture, Q, Cribbs, A, Rao, S, Philpott, M, Snelling, S, Knowles, H
Formaat:	Journal article
Taal:	English
Gepubliceerd in:	Springer Nature 2021

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