Loss of mutual protection between human osteoclasts and chondrocytes in damaged joints initiates osteoclast-mediated cartilage degradation by MMPs
Osteoclasts are multinucleated, bone-resorbing cells. However, they also digest cartilage during skeletal maintenance, development and in degradative conditions including osteoarthritis, rheumatoid arthritis and primary bone sarcoma. This study explores the mechanisms behind the osteoclast–cartilage...
Váldodahkkit: | Larrouture, Q, Cribbs, A, Rao, S, Philpott, M, Snelling, S, Knowles, H |
---|---|
Materiálatiipa: | Journal article |
Giella: | English |
Almmustuhtton: |
Springer Nature
2021
|
Geahča maid
-
Osteoclasts are multinucleated cells that degrade cartilage as well as bone
Dahkki: Larrouture, Q, et al.
Almmustuhtton: (2018) -
Osteoclasts are multinucleated cells that degrade cartilage as well as bone
Dahkki: Larrouture, QC
Almmustuhtton: (2019) -
Osteoclasts degrade bone and cartilage knee joint compartments through different resorption processes
Dahkki: Henrik Löfvall, et al.
Almmustuhtton: (2018-04-01) -
Osteoclast-associated receptor blockade prevents articular cartilage destruction via chondrocyte apoptosis regulation
Dahkki: Doo Ri Park, et al.
Almmustuhtton: (2020-08-01) -
Chondroclasts are mature osteoclasts which are capable of cartilage matrix resorption
Dahkki: Knowles, H, et al.
Almmustuhtton: (2012)