Immune therapy in inflammatory bowel disease and models of colitis.
BACKGROUND: A proliferation of animal models has not only improved our understanding of inflammatory bowel disease, it has also formed the basis of new treatment strategies. METHODS: A search was conducted using the National Library of Medicine for articles discussing immune therapies for inflammato...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
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2001
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| _version_ | 1826282397801381888 |
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| author | Singh, B Powrie, F Mortensen, N |
| author_facet | Singh, B Powrie, F Mortensen, N |
| author_sort | Singh, B |
| collection | OXFORD |
| description | BACKGROUND: A proliferation of animal models has not only improved our understanding of inflammatory bowel disease, it has also formed the basis of new treatment strategies. METHODS: A search was conducted using the National Library of Medicine for articles discussing immune therapies for inflammatory bowel disease. This was supplemented by findings from the authors' own laboratory. RESULTS: An overview of the different animal models is presented. These models are used to highlight the recent human trials of immune therapies. Potential future therapies are also discussed. CONCLUSION: Immune therapies have altered the management of patients with inflammatory bowel disease. In future they will influence not only the indications for surgery but also its timing and outcome. |
| first_indexed | 2024-03-07T00:43:14Z |
| format | Journal article |
| id | oxford-uuid:83c765df-2826-42fd-982b-a2abe8f9d30d |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T00:43:14Z |
| publishDate | 2001 |
| record_format | dspace |
| spelling | oxford-uuid:83c765df-2826-42fd-982b-a2abe8f9d30d2022-03-26T21:46:28ZImmune therapy in inflammatory bowel disease and models of colitis.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:83c765df-2826-42fd-982b-a2abe8f9d30dEnglishSymplectic Elements at Oxford2001Singh, BPowrie, FMortensen, NBACKGROUND: A proliferation of animal models has not only improved our understanding of inflammatory bowel disease, it has also formed the basis of new treatment strategies. METHODS: A search was conducted using the National Library of Medicine for articles discussing immune therapies for inflammatory bowel disease. This was supplemented by findings from the authors' own laboratory. RESULTS: An overview of the different animal models is presented. These models are used to highlight the recent human trials of immune therapies. Potential future therapies are also discussed. CONCLUSION: Immune therapies have altered the management of patients with inflammatory bowel disease. In future they will influence not only the indications for surgery but also its timing and outcome. |
| spellingShingle | Singh, B Powrie, F Mortensen, N Immune therapy in inflammatory bowel disease and models of colitis. |
| title | Immune therapy in inflammatory bowel disease and models of colitis. |
| title_full | Immune therapy in inflammatory bowel disease and models of colitis. |
| title_fullStr | Immune therapy in inflammatory bowel disease and models of colitis. |
| title_full_unstemmed | Immune therapy in inflammatory bowel disease and models of colitis. |
| title_short | Immune therapy in inflammatory bowel disease and models of colitis. |
| title_sort | immune therapy in inflammatory bowel disease and models of colitis |
| work_keys_str_mv | AT singhb immunetherapyininflammatoryboweldiseaseandmodelsofcolitis AT powrief immunetherapyininflammatoryboweldiseaseandmodelsofcolitis AT mortensenn immunetherapyininflammatoryboweldiseaseandmodelsofcolitis |