The effect of clonidine and bright light on plasma melatonin
We studied the effect of α2-adrenoceptor agonist, clonidine, and bright artificial light (> 2500 lux) on the nocturnal increase in plasma melatonin in normal subjects. Clonidine (1.5 μg/kg, intravenously) was without effect on plasma melatonin concentration. In contrast, bright light treatmen...
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| Format: | Journal article |
| Language: | English |
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1988
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| _version_ | 1797079277411237888 |
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| author | Grasby, P Cowen, P |
| author_facet | Grasby, P Cowen, P |
| author_sort | Grasby, P |
| collection | OXFORD |
| description | We studied the effect of α2-adrenoceptor agonist, clonidine, and bright artificial light (> 2500 lux) on the nocturnal increase in plasma melatonin in normal subjects. Clonidine (1.5 μg/kg, intravenously) was without effect on plasma melatonin concentration. In contrast, bright light treatment abolished the increase in night-time melatonin. Bright light is a simple and effective means of altering melatonin secretion in humans. |
| first_indexed | 2024-03-07T00:43:30Z |
| format | Journal article |
| id | oxford-uuid:83dba7bb-d947-45b3-b080-1e8062044482 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T00:43:30Z |
| publishDate | 1988 |
| record_format | dspace |
| spelling | oxford-uuid:83dba7bb-d947-45b3-b080-1e80620444822022-03-26T21:47:04ZThe effect of clonidine and bright light on plasma melatoninJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:83dba7bb-d947-45b3-b080-1e8062044482EnglishSymplectic Elements at Oxford1988Grasby, PCowen, PWe studied the effect of α2-adrenoceptor agonist, clonidine, and bright artificial light (> 2500 lux) on the nocturnal increase in plasma melatonin in normal subjects. Clonidine (1.5 μg/kg, intravenously) was without effect on plasma melatonin concentration. In contrast, bright light treatment abolished the increase in night-time melatonin. Bright light is a simple and effective means of altering melatonin secretion in humans. |
| spellingShingle | Grasby, P Cowen, P The effect of clonidine and bright light on plasma melatonin |
| title | The effect of clonidine and bright light on plasma melatonin |
| title_full | The effect of clonidine and bright light on plasma melatonin |
| title_fullStr | The effect of clonidine and bright light on plasma melatonin |
| title_full_unstemmed | The effect of clonidine and bright light on plasma melatonin |
| title_short | The effect of clonidine and bright light on plasma melatonin |
| title_sort | effect of clonidine and bright light on plasma melatonin |
| work_keys_str_mv | AT grasbyp theeffectofclonidineandbrightlightonplasmamelatonin AT cowenp theeffectofclonidineandbrightlightonplasmamelatonin AT grasbyp effectofclonidineandbrightlightonplasmamelatonin AT cowenp effectofclonidineandbrightlightonplasmamelatonin |