The gene encoding the T-box factor Tbx2 is a target for the microphthalmia-associated transcription factor in melanocytes.

Commitment to the melanocyte lineage is characterized by the onset of microphthalmia-associated transcription factor (Mitf) expression. Mitf plays a fundamental role in melanocyte development, with mice lacking Mitf being entirely devoid of pigment cells. In the absence of functional Mitf protein, m...

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Những tác giả chính: Carreira, S, Liu, B, Goding, C
Định dạng: Journal article
Ngôn ngữ:English
Được phát hành: 2000