Untargeted metabolome quantitative trait locus mapping associates variation in urine glycerate to mutant glycerate kinase

Untargeted metabolome quantitative trait locus mapping associates variation in urine glycerate to mutant glycerate kinase

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With successes of genome-wide association studies, molecular phenotyping systems are developed to identify genetically determined disease-associated biomarkers. Genetic studies of the human metabolome are emerging but exclusively apply targeted approaches, which restricts the analysis to a limited n...

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Bibliographic Details
Main Authors:	Cazier, J, Kaisaki, P, Argoud, K, Blaise, B, Veselkov, K, Ebbels, T, Tsang, T, Wang, Y, Bihoreau, M, Mitchell, S, Holmes, E, Lindon, J, Scott, J, Nicholson, J, Dumas, M, Gauguier, D
Format:	Journal article
Language:	English
Published:	2012

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