Substituted aziridines by lithiation-electrophile trapping of terminal aziridines.
[reaction: see text] Regio- and stereoselective deprotonation of N-Bus (Bus = tert-butylsulfonyl)-protected terminal aziridines with lithium 2,2,6,6-tetramethylpiperidide generates a nonstabilized (H-substituted) aziridinyl anion that undergoes in situ or external electrophile trapping under experim...
| Autores principales: | , , |
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| Formato: | Journal article |
| Lenguaje: | English |
| Publicado: |
2005
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| _version_ | 1826282436969889792 |
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| author | Hodgson, D Humphreys, P Ward, J |
| author_facet | Hodgson, D Humphreys, P Ward, J |
| author_sort | Hodgson, D |
| collection | OXFORD |
| description | [reaction: see text] Regio- and stereoselective deprotonation of N-Bus (Bus = tert-butylsulfonyl)-protected terminal aziridines with lithium 2,2,6,6-tetramethylpiperidide generates a nonstabilized (H-substituted) aziridinyl anion that undergoes in situ or external electrophile trapping under experimentally straightforward conditions to give trans-disubstituted aziridines in good to excellent yields. |
| first_indexed | 2024-03-07T00:43:50Z |
| format | Journal article |
| id | oxford-uuid:83f4bae1-9486-4607-9334-5610a3f8c243 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T00:43:50Z |
| publishDate | 2005 |
| record_format | dspace |
| spelling | oxford-uuid:83f4bae1-9486-4607-9334-5610a3f8c2432022-03-26T21:47:47ZSubstituted aziridines by lithiation-electrophile trapping of terminal aziridines.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:83f4bae1-9486-4607-9334-5610a3f8c243EnglishSymplectic Elements at Oxford2005Hodgson, DHumphreys, PWard, J[reaction: see text] Regio- and stereoselective deprotonation of N-Bus (Bus = tert-butylsulfonyl)-protected terminal aziridines with lithium 2,2,6,6-tetramethylpiperidide generates a nonstabilized (H-substituted) aziridinyl anion that undergoes in situ or external electrophile trapping under experimentally straightforward conditions to give trans-disubstituted aziridines in good to excellent yields. |
| spellingShingle | Hodgson, D Humphreys, P Ward, J Substituted aziridines by lithiation-electrophile trapping of terminal aziridines. |
| title | Substituted aziridines by lithiation-electrophile trapping of terminal aziridines. |
| title_full | Substituted aziridines by lithiation-electrophile trapping of terminal aziridines. |
| title_fullStr | Substituted aziridines by lithiation-electrophile trapping of terminal aziridines. |
| title_full_unstemmed | Substituted aziridines by lithiation-electrophile trapping of terminal aziridines. |
| title_short | Substituted aziridines by lithiation-electrophile trapping of terminal aziridines. |
| title_sort | substituted aziridines by lithiation electrophile trapping of terminal aziridines |
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