Comprehensive assessment of variation at the transforming growth factor beta type 1 receptor locus and colorectal cancer predisposition.

The role of transforming growth factor beta receptor type 1 (TGFBR1) polymorphisms, particularly a coding CGC insertion (rs11466445, TGFBR1*6A/9A) in exon 1, has been extensively investigated in regard to colorectal cancer (CRC) risk. These investigations have generated conflicting results. More rec...

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Detalhes bibliográficos
Principais autores: Carvajal-Carmona, L, Churchman, M, Bonilla, C, Walther, A, Lefèvre, J, Kerr, D, Dunlop, M, Houlston, R, Bodmer, W, Tomlinson, I
Formato: Journal article
Idioma:English
Publicado em: 2010