Haemoglobin C and S role in acquired immunity against Plasmodium falciparum malaria.

Haemoglobin C and S role in acquired immunity against Plasmodium falciparum malaria.

A recently proposed mechanism of protection for haemoglobin C (HbC; beta6Glu-->Lys) links an abnormal display of PfEMP1, an antigen involved in malaria pathogenesis, on the surface of HbC infected erythrocytes together with the observation of reduced cytoadhesion of parasitized erythrocytes a...

תיאור מלא

מידע ביבליוגרפי
Main Authors:	Verra, F, Simpore, J, Warimwe, G, Tetteh, K, Howard, T, Osier, F, Bancone, G, Avellino, P, Blot, I, Fegan, G, Bull, P, Williams, T, Conway, D, Marsh, K, Modiano, D
פורמט:	Journal article
שפה:	English
יצא לאור:	Public Library of Science 2007

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Errattum: Haemoglobin S and haemoglobin C: 'Quick but costly' versus 'slow but gratis' genetic adaptations to Plasmodium falciparum malaria (Human Molecular Genetics (2008) vol. 17 (6) (789-799) 10.1093/hmg/ ddm350)
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