Haemoglobin C and S role in acquired immunity against Plasmodium falciparum malaria.

Haemoglobin C and S role in acquired immunity against Plasmodium falciparum malaria.

A recently proposed mechanism of protection for haemoglobin C (HbC; beta6Glu-->Lys) links an abnormal display of PfEMP1, an antigen involved in malaria pathogenesis, on the surface of HbC infected erythrocytes together with the observation of reduced cytoadhesion of parasitized erythrocytes a...

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Detalhes bibliográficos
Main Authors:	Verra, F, Simpore, J, Warimwe, G, Tetteh, K, Howard, T, Osier, F, Bancone, G, Avellino, P, Blot, I, Fegan, G, Bull, P, Williams, T, Conway, D, Marsh, K, Modiano, D
Formato:	Journal article
Idioma:	English
Publicado em:	Public Library of Science 2007

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