Haemoglobin C and S role in acquired immunity against Plasmodium falciparum malaria.
A recently proposed mechanism of protection for haemoglobin C (HbC; beta6Glu-->Lys) links an abnormal display of PfEMP1, an antigen involved in malaria pathogenesis, on the surface of HbC infected erythrocytes together with the observation of reduced cytoadhesion of parasitized erythrocytes a...
Những tác giả chính: | Verra, F, Simpore, J, Warimwe, G, Tetteh, K, Howard, T, Osier, F, Bancone, G, Avellino, P, Blot, I, Fegan, G, Bull, P, Williams, T, Conway, D, Marsh, K, Modiano, D |
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Định dạng: | Journal article |
Ngôn ngữ: | English |
Được phát hành: |
Public Library of Science
2007
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Haemoglobin S and haemoglobin C: 'quick but costly' versus 'slow but gratis' genetic adaptations to Plasmodium falciparum malaria (vol 17, pg 789, 2008)
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Errattum: Haemoglobin S and haemoglobin C: 'Quick but costly' versus 'slow but gratis' genetic adaptations to Plasmodium falciparum malaria (Human Molecular Genetics (2008) vol. 17 (6) (789-799) 10.1093/hmg/ ddm350)
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Được phát hành: (2008)