Digital analysis of protein properties by an ensemble of DNA quadruplexes.

Here we show how different principles developed in the area of molecular logic gates can be applied to diagnostic technologies for proteins. Simultaneous operation of YES NOT and PASS 1 logic gates, produced by a protein sensing ensemble of DNA G-quadruplexes, is used to encode concentration levels...

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Bibliographic Details
Main Authors: Margulies, D, Hamilton, A
Format: Journal article
Language:English
Published: 2009