TNF autovaccination induces self anti-TNF antibodies and inhibits metastasis in a murine melanoma model.

TNF is a proinflammatory cytokine involved in the pathogenesis of chronic inflammatory diseases, but also in metastasis in certain types of cancer. In terms of therapy, TNF is targeted by anti-TNF neutralising monoclonal antibodies or soluble TNF receptors. Recently, a novel strategy based on the ge...

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書目詳細資料
Main Authors: Waterston, A, Salway, F, Andreakos, E, Butler, D, Feldmann, M, Coombes, R
格式: Journal article
語言:English
出版: Nature Publishing Group 2004