Genome-wide screen identifies new candidate genes associated with artemisinin susceptibility in Plasmodium falciparum in Kenya
Early identification of causal genetic variants underlying antimalarial drug resistance could provide robust epidemiological tools for timely public health interventions. Using a novel natural genetics strategy for mapping novel candidate genes we analyzed >75,000 high quality single nucleoti...
मुख्य लेखकों: | Borrmann, S, Straimer, J, Mwai, L, Abdi, A, Rippert, A, Okombo, J, Muriithi, S, Sasi, P, Kortok, M, Lowe, B, Campino, S, Assefa, S, Auburn, S, Manske, M, Maslen, G, Peshu, N, Kwiatkowski, D, Marsh, K, Nzila, A, Clark, T |
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स्वरूप: | Journal article |
भाषा: | English |
प्रकाशित: |
Springer Nature
2013
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समान संसाधन
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Declining Responsiveness of Plasmodium falciparum Infections to Artemisinin-Based Combination Treatments on the Kenyan Coast.
द्वारा: Borrmann, S, और अन्य
प्रकाशित: (2011) -
Declining responsiveness of Plasmodium falciparum infections to artemisinin-based combination treatments on the Kenyan coast.
द्वारा: Steffen Borrmann, और अन्य
प्रकाशित: (2011-01-01) -
In vitro activities of piperaquine, lumefantrine, and dihydroartemisinin in Kenyan Plasmodium falciparum isolates and polymorphisms in pfcrt and pfmdr1.
द्वारा: Mwai, L, और अन्य
प्रकाशित: (2009) -
Analysis of Plasmodium falciparum diversity in natural infections by deep sequencing
द्वारा: Manske, M, और अन्य
प्रकाशित: (2012) -
The MSPDBL2 codon 591 polymorphism is associated with lumefantrine in vitro drug responses in Plasmodium falciparum isolates from Kilifi, Kenya.
द्वारा: Ochola-Oyier, L, और अन्य
प्रकाशित: (2014)