Ethical issues in Nipah virus control and research: addressing a neglected disease

Nipah virus is a priority pathogen that is receiving increasing attention among scientists and in work on epidemic preparedness. Despite this trend, there has been almost no bioethical work examining ethical considerations surrounding the epidemiology, prevention, and treatment of Nipah virus or res...

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Main Authors: Johnson, T, Jamrozik, E, Hurst, T, Cheah, PY, Parker, M
Format: Journal article
Language:English
Published: BMJ Publishing Group 2023
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author Johnson, T
Jamrozik, E
Hurst, T
Cheah, PY
Parker, M
author_facet Johnson, T
Jamrozik, E
Hurst, T
Cheah, PY
Parker, M
author_sort Johnson, T
collection OXFORD
description Nipah virus is a priority pathogen that is receiving increasing attention among scientists and in work on epidemic preparedness. Despite this trend, there has been almost no bioethical work examining ethical considerations surrounding the epidemiology, prevention, and treatment of Nipah virus or research that has already begun into animal and human vaccines. In this paper, we advance the case for further work on Nipah virus disease in public health ethics due to the distinct issues it raises concerning communication about the modes of transmission, the burdens of public health surveillance, the recent use of stringent public health measures during epidemics, and social or religious norms intersecting with preventive measures. We also advance the case for further work on Nipah virus disease in research ethics, given ethical issues surrounding potential vaccine trials for a high-fatality disease with sporadic spillover events, the different local contexts where trials may occur, and the potential use of unproven therapeutics during outbreaks. Further bioethics work may help to ensure that research and public health interventions for Nipah virus disease are ethically acceptable and more likely to be effective.
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spelling oxford-uuid:842167b2-9437-4c7d-a23a-723935f761d02025-02-03T13:38:15ZEthical issues in Nipah virus control and research: addressing a neglected diseaseJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:842167b2-9437-4c7d-a23a-723935f761d0EnglishSymplectic ElementsBMJ Publishing Group2023Johnson, TJamrozik, EHurst, TCheah, PYParker, MNipah virus is a priority pathogen that is receiving increasing attention among scientists and in work on epidemic preparedness. Despite this trend, there has been almost no bioethical work examining ethical considerations surrounding the epidemiology, prevention, and treatment of Nipah virus or research that has already begun into animal and human vaccines. In this paper, we advance the case for further work on Nipah virus disease in public health ethics due to the distinct issues it raises concerning communication about the modes of transmission, the burdens of public health surveillance, the recent use of stringent public health measures during epidemics, and social or religious norms intersecting with preventive measures. We also advance the case for further work on Nipah virus disease in research ethics, given ethical issues surrounding potential vaccine trials for a high-fatality disease with sporadic spillover events, the different local contexts where trials may occur, and the potential use of unproven therapeutics during outbreaks. Further bioethics work may help to ensure that research and public health interventions for Nipah virus disease are ethically acceptable and more likely to be effective.
spellingShingle Johnson, T
Jamrozik, E
Hurst, T
Cheah, PY
Parker, M
Ethical issues in Nipah virus control and research: addressing a neglected disease
title Ethical issues in Nipah virus control and research: addressing a neglected disease
title_full Ethical issues in Nipah virus control and research: addressing a neglected disease
title_fullStr Ethical issues in Nipah virus control and research: addressing a neglected disease
title_full_unstemmed Ethical issues in Nipah virus control and research: addressing a neglected disease
title_short Ethical issues in Nipah virus control and research: addressing a neglected disease
title_sort ethical issues in nipah virus control and research addressing a neglected disease
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