Malignant pleural effusion: From diagnostics to therapeutics.

Malignant pleural effusion is a common complication of cancer and denotes a poor prognosis. It usually presents with dyspnea and a unilateral large pleural effusion. Thoracic computed tomography scans and ultrasound are helpful in distinguishing malignant from benign effusions. Pleural fluid cytolog...

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Main Authors: Asciak, R, Rahman, N
Format: Journal article
Language:English
Published: Elsevier 2017
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author Asciak, R
Rahman, N
author_facet Asciak, R
Rahman, N
author_sort Asciak, R
collection OXFORD
description Malignant pleural effusion is a common complication of cancer and denotes a poor prognosis. It usually presents with dyspnea and a unilateral large pleural effusion. Thoracic computed tomography scans and ultrasound are helpful in distinguishing malignant from benign effusions. Pleural fluid cytology is diagnostic in about 60% of cases. In cytology-negative disease, pleural biopsies are helpful. Current management is palliative. Previously, first-line treatment for recurrent symptomatic malignant pleural effusion was chest drain insertion and talc pleurodesis, with indwelling pleural catheter insertion reserved for patients with trapped lung or failed talc pleurodesis. However, catheter insertion is an increasingly acceptable first-line treatment.
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spelling oxford-uuid:843302f2-46b5-44f0-ab48-7102b6a508b92022-03-26T21:49:37ZMalignant pleural effusion: From diagnostics to therapeutics.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:843302f2-46b5-44f0-ab48-7102b6a508b9EnglishSymplectic Elements at OxfordElsevier2017Asciak, RRahman, NMalignant pleural effusion is a common complication of cancer and denotes a poor prognosis. It usually presents with dyspnea and a unilateral large pleural effusion. Thoracic computed tomography scans and ultrasound are helpful in distinguishing malignant from benign effusions. Pleural fluid cytology is diagnostic in about 60% of cases. In cytology-negative disease, pleural biopsies are helpful. Current management is palliative. Previously, first-line treatment for recurrent symptomatic malignant pleural effusion was chest drain insertion and talc pleurodesis, with indwelling pleural catheter insertion reserved for patients with trapped lung or failed talc pleurodesis. However, catheter insertion is an increasingly acceptable first-line treatment.
spellingShingle Asciak, R
Rahman, N
Malignant pleural effusion: From diagnostics to therapeutics.
title Malignant pleural effusion: From diagnostics to therapeutics.
title_full Malignant pleural effusion: From diagnostics to therapeutics.
title_fullStr Malignant pleural effusion: From diagnostics to therapeutics.
title_full_unstemmed Malignant pleural effusion: From diagnostics to therapeutics.
title_short Malignant pleural effusion: From diagnostics to therapeutics.
title_sort malignant pleural effusion from diagnostics to therapeutics
work_keys_str_mv AT asciakr malignantpleuraleffusionfromdiagnosticstotherapeutics
AT rahmann malignantpleuraleffusionfromdiagnosticstotherapeutics