Renal cells activate the platelet receptor CLEC-2 through podoplanin

We have recently shown that the C-type lectin-like receptor, CLEC-2, is expressed on platelets and that it mediates powerful platelet aggregation by the snake venom toxin rhodocytin. In addition, we have provided indirect evidence for an endogenous ligand for CLEC-2 in renal cells expressing HIV-1....

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Príomhchruthaitheoirí: Christou, C, Pearce, A, Watson, A, Mistry, A, Pollitt, A, Fenton-May, A, Johnson, L, Jackson, D, Watson, S, O'Callaghan, C
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: 2008