Diagnosis of scrub typhus.
Scrub typhus is transmitted by trombiculid mites and is endemic to East and Southeast Asia and Northern Australia. The clinical syndrome classically consists of a fever, rash, and eschar, but scrub typhus also commonly presents as an undifferentiated fever that requires laboratory confirmation of th...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
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2010
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| _version_ | 1826282523076853760 |
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| author | Koh, G Maude, R Paris, D Newton, P Blacksell, S |
| author_facet | Koh, G Maude, R Paris, D Newton, P Blacksell, S |
| author_sort | Koh, G |
| collection | OXFORD |
| description | Scrub typhus is transmitted by trombiculid mites and is endemic to East and Southeast Asia and Northern Australia. The clinical syndrome classically consists of a fever, rash, and eschar, but scrub typhus also commonly presents as an undifferentiated fever that requires laboratory confirmation of the diagnosis, usually by indirect fluorescent antibody (IFA) assay. We discuss the limitations of IFA, debate the value of other methods based on antigen detection and nucleic acid amplification, and outline recommendations for future study. |
| first_indexed | 2024-03-07T00:45:08Z |
| format | Journal article |
| id | oxford-uuid:8461e2e2-c734-49ce-b8ce-5e59efdd0f71 |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-07T00:45:08Z |
| publishDate | 2010 |
| record_format | dspace |
| spelling | oxford-uuid:8461e2e2-c734-49ce-b8ce-5e59efdd0f712022-03-26T21:50:40ZDiagnosis of scrub typhus.Journal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:8461e2e2-c734-49ce-b8ce-5e59efdd0f71EnglishSymplectic Elements at Oxford2010Koh, GMaude, RParis, DNewton, PBlacksell, SScrub typhus is transmitted by trombiculid mites and is endemic to East and Southeast Asia and Northern Australia. The clinical syndrome classically consists of a fever, rash, and eschar, but scrub typhus also commonly presents as an undifferentiated fever that requires laboratory confirmation of the diagnosis, usually by indirect fluorescent antibody (IFA) assay. We discuss the limitations of IFA, debate the value of other methods based on antigen detection and nucleic acid amplification, and outline recommendations for future study. |
| spellingShingle | Koh, G Maude, R Paris, D Newton, P Blacksell, S Diagnosis of scrub typhus. |
| title | Diagnosis of scrub typhus. |
| title_full | Diagnosis of scrub typhus. |
| title_fullStr | Diagnosis of scrub typhus. |
| title_full_unstemmed | Diagnosis of scrub typhus. |
| title_short | Diagnosis of scrub typhus. |
| title_sort | diagnosis of scrub typhus |
| work_keys_str_mv | AT kohg diagnosisofscrubtyphus AT mauder diagnosisofscrubtyphus AT parisd diagnosisofscrubtyphus AT newtonp diagnosisofscrubtyphus AT blacksells diagnosisofscrubtyphus |