SNARE protein redistribution and synaptic failure in a transgenic mouse model of Parkinson's disease.

The pre-synaptic protein alpha-synuclein is the main component of Lewy bodies and Lewy neurites, the defining neuropathological characteristics of Parkinson's disease and dementia with Lewy bodies. Mutations in the alpha-synuclein gene cause familial forms of Parkinson's disease and dement...

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Bibliographic Details
Main Authors: Garcia-Reitböck, P, Anichtchik, O, Bellucci, A, Iovino, M, Ballini, C, Fineberg, E, Ghetti, B, Della Corte, L, Spano, P, Tofaris, G, Goedert, M, Spillantini, MG
Format: Journal article
Language:English
Published: 2010