Reduced phospholamban phosphorylation is associated with impaired relaxation in left ventricular myocytes from neuronal NO synthase-deficient mice.
Stimulation of nitric oxide (NO) release from the coronary endothelium facilitates myocardial relaxation via a cGMP-dependent reduction in myofilament Ca2+ sensitivity. Recent evidence suggests that NO released by a neuronal NO synthase (nNOS) in the myocardium can also hasten left ventricular relax...
Những tác giả chính: | Zhang, Y, Zhang, M, Sears, C, Emanuel, K, Redwood, C, El-Armouche, A, Kranias, E, Casadei, B |
---|---|
Định dạng: | Journal article |
Ngôn ngữ: | English |
Được phát hành: |
2008
|
Những quyển sách tương tự
-
Regulation of myocardial relaxation by neuronal NOS: Role phospholamban phosphorylation and phosphatase activity
Bằng: Zhang, Y, et al.
Được phát hành: (2007) -
Cardiac nNOS regulates myocardial relaxation by stimulating phospholamban phosphorylation
Bằng: Zhang, Y, et al.
Được phát hành: (2005) -
Cardiac nNOS regulates myocardial relaxation by stimulating phospholamban phosphorylation
Bằng: Zhang, Y, et al.
Được phát hành: (2005) -
Reduced phospholamban phosphorylation is responsible for impaired myocardial relaxation in nNOS(-/-) mice
Bằng: Zhang, Y, et al.
Được phát hành: (2005) -
Reduced phospholamban phosphorylation is responsible for impaired myocardial relaxation in nNOS(-/-) mice
Bằng: Zhang, Y, et al.
Được phát hành: (2006)