Normal responsiveness of CTLA-4-deficient anti-viral cytotoxic T cells.
CTLA-4 has been proposed to negatively regulate immune responses, and mice deficient for CTLA-4 expression succumb to a lymphoproliferative disorder within a few weeks after birth. This study assessed the responsiveness of CTLA-4-deficient T cells expressing a class I-restricted TCR specific for lym...
| Главные авторы: | , , , , , |
|---|---|
| Формат: | Journal article |
| Язык: | English |
| Опубликовано: |
1998
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