Changes in malaria parasite drug resistance in an endemic population over a 25-year period with resulting genomic evidence of selection.

Changes in malaria parasite drug resistance in an endemic population over a 25-year period with resulting genomic evidence of selection.

BACKGROUND:  Analysis of genome-wide polymorphism in many organisms has potential to identify genes under recent selection. However, data on historical allele frequency changes are rarely available for direct confirmation. METHODS:  We genotyped single nucleotide polymorphisms (SNPs) in 4 Plasmodium...

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التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Nwakanma, D, Duffy, C, Amambua-Ngwa, A, Oriero, E, Bojang, K, Pinder, M, Drakeley, C, Sutherland, C, Milligan, P, Macinnis, B, Kwiatkowski, D, Clark, T, Greenwood, B, Conway, D
التنسيق: Journal article
اللغة:English
منشور في: University of Chicago Press 2014

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