Bacteria exposed biliary epithelium and liver B cells activate intrahepatic mait cells in an MR1-dependent manner

Bacteria exposed biliary epithelium and liver B cells activate intrahepatic mait cells in an MR1-dependent manner

Mucosal-Associated Invariant T (MAIT) cells are innate-like T cells characterised by the invariant TCR-chain, Vα7.2-Jα33, and are restricted by MR1, which presents bacterial vitamin B metabolites. They are important for antibacterial immunity at mucosal sites; however, detailed characteristics of li...

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Bibliographic Details
Main Authors: Jeffery, H, van Wilgenburg, B, Kurioka, A, Parekh, K, Stirling, K, Roberts, S, Dutton, E, Hunter, S, Geh, D, Braitch, M, Rajanayagam, J, Iqbal, T, Pinkney, T, Brown, R, Withers, D, Adams, D, Klenerman, P, Oo, Y
Format: Journal article
Language:English
Published: Elsevier 2015

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