Functional investigation of troponin with the homozygous HCM mutation, TNNT2 K280N, obtained from an explanted heart

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Bayliss, C, Messer, A, Leung, M, Ward, D, Van Der Velden, J, Poggesi, C, Redwood, C, Marston, S
التنسيق:	Conference item
منشور في:	2012

The HCM-associated cardiac Troponin T mutation K280N causes reduced responsiveness to protein kinase A
حسب: Van Der Velden, J, وآخرون
منشور في: (2012)

The HCM-Associated Cardiac Troponin T Mutation K280N Increases the Energetic Cost of Tension Generation in Human Cardiac Myofibrils
حسب: Ferrara, C, وآخرون
منشور في: (2013)

The effect of HCM mutations in troponin T and troponin I on the calcium binding of human cardiac troponin
حسب: Redwood, C, وآخرون
منشور في: (2001)

Low expression of the K280N TNNT2 mutation is sufficient to increase basal myofilament activation in human hypertrophy cardiomyopathy
حسب: Vasco Sequeira, وآخرون
منشور في: (2022-09-01)

Mutations in troponin T associated with Hypertrophic Cardiomyopathy increase Ca2+-sensitivity and suppress the modulation of Ca2+-sensitivity by troponin I phosphorylation
حسب: Messer, A, وآخرون
منشور في: (2016)

A revised method of troponin exchange in permeabilised cardiac trabeculae using vanadate: functional consequences of a HCM-causing mutation in troponin I.
حسب: Preston, L, وآخرون
منشور في: (2006)

In vitro motility studies of HCM and DCM mutations in cardiac muscle actin
حسب: Dyer, E, وآخرون
منشور في: (2007)

Myofibrillar Ca(2+) sensitivity is uncoupled from troponin I phosphorylation in hypertrophic obstructive cardiomyopathy due to abnormal troponin T.
حسب: Bayliss, C, وآخرون
منشور في: (2013)

A Novel Homozygous Intronic Variant in TNNT2 Associates With Feline Cardiomyopathy
حسب: James W. McNamara, وآخرون
منشور في: (2020-11-01)

Evidence for haploinsufficiency as the mechanism of action of MyBP-C mutations that cause HCM
حسب: Carballo, S, وآخرون
منشور في: (2008)

HCM and DCM mutations in thin filament proteins have opposite effects on in vitro motility
حسب: Marston, S, وآخرون
منشور في: (2002)

Cardiac Troponin T (TNNT2) plays a potential oncogenic role in colorectal carcinogenesis
حسب: Yifan Liu, وآخرون
منشور في: (2023-07-01)

HCM and DCM mutations in thin filament proteins have opposite effects on regulation of contractility in vitro
حسب: Redwood, C, وآخرون
منشور في: (2003)

Correction: Cardiac Troponin T (TNNT2) plays a potential oncogenic role in colorectal carcinogenesis
حسب: Yifan Liu, وآخرون
منشور في: (2023-12-01)

HCM and DCM mutations in cardiac thin filament proteins have opposite effects on the regulation of contractility in vitro
حسب: Redwood, C, وآخرون
منشور في: (2003)

Mouse HCM Model Expression E99K ACTC Mutation Reproduces the Clinical HCM Phenotype
حسب: Song, W, وآخرون
منشور في: (2009)

Genotype-Driven Pathogenesis of Atrial Fibrillation in Hypertrophic Cardiomyopathy: The Case of Different TNNT2 Mutations
حسب: Josè Manuel Pioner, وآخرون
منشور في: (2022-04-01)

Investigation of troponin I mutations causing familial hypertrophic cardiomyopathy
حسب: Abdulrazzak, H, وآخرون
منشور في: (2001)

Functional effects of mutations in troponin T and tropomyosin which cause dilated cardiomyopathy
حسب: Robinson, P, وآخرون
منشور في: (2003)

Pressure Overload Is Associated With Low Levels of Troponin I and Myosin Binding Protein C Phosphorylation in the Hearts of Patients With Aortic Stenosis
حسب: O’neal Copeland, وآخرون
منشور في: (2020-03-01)

Increased Myocardial Oxygen Consumption Precedes Contractile Dysfunction in Hypertrophic Cardiomyopathy Caused by Pathogenic TNNT2 Gene Variants
حسب: Rahana Y. Parbhudayal, وآخرون
منشور في: (2020-04-01)

Comparison of the functional effects of mutations in troponin T which cause dilated and hypertrophic cardiomyopathies
حسب: Robinson, P, وآخرون
منشور في: (2002)

Nutraceuticals silybin B, resveratrol, and epigallocatechin-3 gallate-bind to cardiac muscle troponin to restore the loss of lusitropy caused by cardiomyopathy mutations in vitro, in vivo, and in silico
حسب: Yang, Z, وآخرون
منشور في: (2024)

Interaction analyses elucidate the pathophysiology of HCM-causing missense mutations in cardiac myosin binding protein-C.
حسب: Moolman-Smook, J, وآخرون
منشور في: (2001)

Structure-function relationships of eight mutations in troponin and tropomyosin that cause dilated cardiomyopathy
حسب: Mirza, M, وآخرون
منشور في: (2004)

DCM troponin C mutant Gly159Asp blunts the response to troponin phosphorylation.
حسب: Preston, L, وآخرون
منشور في: (2007)

Mutations in fast skeletal troponin I, troponin T and beta-tropomyosin that cause distal arthrogryposis all enhance thin filament activation
حسب: Robinson, P, وآخرون
منشور في: (2005)

Two mutations in troponin I that cause hypertrophic cardiomyopathy have contrasting effects on cardiac muscle contractility.
حسب: Burton, D, وآخرون
منشور في: (2002)

A comparative study of mutation screening of sarcomeric genes (MYBPC3, MYH7, TNNT2) using single gene approach versus targeted gene panel next generation sequencing in a cohort of HCM patients in Egypt
حسب: Heba Sh. Kassem, وآخرون
منشور في: (2017-10-01)

Dilated cardiomyopathy causing mutations in cardiac troponin T (TNT), cardiac troponin C (TNC), and alpha tropomyosin (TM) reduce CA(2+) sensitivity and maximum calcium activation
حسب: Redwood, C, وآخرون
منشور في: (2004)

Using fluorescence emission spectroscopy to asses the Ca2+ affinity of reconstituted troponin and thin filaments containing cardiomyopathy causing mutations of troponin and alpha-tropomyosin
حسب: Robinson, P, وآخرون
منشور في: (2007)

Slower calcium handling balances faster cross-bridge cycling in human MYBPC3 HCM
حسب: Pioner, JM, وآخرون
منشور في: (2023)

Mutations in fast skeletal troponin I, troponin T, and beta-tropomyosin that cause distal arthrogryposis all increase contractile function.
حسب: Robinson, P, وآخرون
منشور في: (2007)

Investigating the role of uncoupling of Troponin I phosphorylation from changes in myofibrillar Ca2+-sensitivity in the pathogenesis of Cardiomyopathy
حسب: Andrew Easton Messer, وآخرون
منشور في: (2014-08-01)

Nutraceuticals silybin B, resveratrol, and epigallocatechin-3 gallate-bind to cardiac muscle troponin to restore the loss of lusitropy caused by cardiomyopathy mutations in vitro, in vivo, and in silico
حسب: Zeyu Yang, وآخرون
منشور في: (2024-12-01)

Altered inhibitory and troponin C-binding activities in cardiac troponin I mutants known to cause hypertrophic cardiomyopathy
حسب: Elliott, K, وآخرون
منشور في: (2000)

Alterations in thin filament regulation induced by a human cardiac troponin T mutant that causes dilated cardiomyopathy are distinct from those induced by troponin T mutants that cause hypertrophic cardiomyopathy.
حسب: Robinson, P, وآخرون
منشور في: (2002)

A novel interaction between the C5 and C8 domains of myosin binding protein-C and its modulation by HCM mutations
حسب: Flashman, E, وآخرون
منشور في: (2002)

Effects of hypertrophic cardiomyopathy mutations in troponin I on contractility of skinned cardiac muscle fibres
حسب: Burton, D, وآخرون
منشور في: (2002)

Cardiac Overexpression of XIN Prevents Dilated Cardiomyopathy Caused by TNNT2 ΔK210 Mutation
حسب: Bin Li, وآخرون
منشور في: (2021-06-01)

Functional investigation of troponin with the homozygous HCM mutation, TNNT2 K280N, obtained from an explanted heart

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مواد مشابهة