Immune evasion in malaria: altered peptide ligands of the circumsporozoite protein.
T cells are central to immunity in malaria. CD4+ helper T cells favour the generation of high-affinity antibodies that are effective against blood stages and they are necessary to establish immunological memory. The intrahepatic stage of infection can be eliminated by specific CD8+ cytotoxic T cells...
Main Authors: | Plebanski, M, Lee, E, Hill, A |
---|---|
Format: | Journal article |
Sprog: | English |
Udgivet: |
1997
|
Lignende værker
-
Altered peptide ligands narrow the repertoire of cellular immune responses by interfering with T-cell priming.
af: Plebanski, M, et al.
Udgivet: (1999) -
Malaria oocysts require circumsporozoite protein to evade mosquito immunity
af: Feng Zhu, et al.
Udgivet: (2022-06-01) -
Sterile protection against malaria is independent of immune responses to the circumsporozoite protein.
af: Anne Charlotte Grüner, et al.
Udgivet: (2007-12-01) -
Antibody Targets and Properties for Complement-Fixation Against the Circumsporozoite Protein in Malaria Immunity
af: Liriye Kurtovic, et al.
Udgivet: (2021-12-01) -
Naturally exposed populations differ in their T1 and T2 responses to the circumsporozoite protein of Plasmodium falciparum.
af: Reece, W, et al.
Udgivet: (2002)