Immune evasion in malaria: altered peptide ligands of the circumsporozoite protein.
T cells are central to immunity in malaria. CD4+ helper T cells favour the generation of high-affinity antibodies that are effective against blood stages and they are necessary to establish immunological memory. The intrahepatic stage of infection can be eliminated by specific CD8+ cytotoxic T cells...
Autori principali: | Plebanski, M, Lee, E, Hill, A |
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Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
1997
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