Distinct mechanisms regulate Lck spatial organization in activated T cells
Phosphorylation of the T cell receptor (TCR) by the kinase Lck is the first detectable signaling event upon antigen engagement. The distribution of Lck within the plasma membrane, its conformational state, kinase activity, and protein–protein interactions all contribute to determine how efficiently...
Автори: | Kapoor-Kaushik, N, Hinde, E, Compeer, E, Yamamoto, Y, Kraus, F, Yang, Z, Lou, J, Pageon, S, Tabarin, T, Gaus, K, Rossy, J |
---|---|
Формат: | Journal article |
Мова: | English |
Опубліковано: |
Frontiers Media
2016
|
Схожі ресурси
Схожі ресурси
-
A mobile endocytic network connects clathrin-independent receptor endocytosis to recycling and promotes T cell activation
за авторством: Compeer, E, та інші
Опубліковано: (2018) -
Molecular mechanisms of Lck activity regulation in human peripheral blood T lymphocytes
за авторством: Irles, C, та інші
Опубліковано: (2004) -
Lck and the nature of the T cell receptor trigger
за авторством: Davis, S, та інші
Опубліковано: (2011) -
Lck and the nature of the T cell receptor trigger.
за авторством: Davis, S, та інші
Опубліковано: (2011) -
Developmental regulation of Lck targeting to the CD8 coreceptor controls signaling in naive and memory T cells.
за авторством: Bachmann, M, та інші
Опубліковано: (1999)