Conditional knockout of GCH1 in leukocytes and endothelial cells: A novel model to study tetrahydrobiopterin-dependent NOS functions in vivo

Conditional knockout of GCH1 in leukocytes and endothelial cells: A novel model to study tetrahydrobiopterin-dependent NOS functions in vivo

מידע ביבליוגרפי
Main Authors:	McNeill, E, Chuaiphichai, S, Crabtree, M, Hale, A, Alp, N, Channon, K
פורמט:	Conference item
יצא לאור:	2012

פריטים דומים

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201 Regulation of INOS Function, Redox State and NRF2 Activation by Macrophage GCH1 and Tetrahydrobiopterin.
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Regulation of iNOS function and cellular redox state by macrophage Gch1 reveals specific requirements for tetrahydrobiopterin in NRF2 activation.
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A requirement for Gch1 and tetrahydrobiopterin in embryonic development.
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Cell-autonomous role of endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation.
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Cell-autonomous role of endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation
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Regulation of mycobacterial infection by macrophage Gch1 and tetrahydrobiopterin
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Regulation of mycobacterial infection by macrophage Gch1 and tetrahydrobiopterin
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303A cell-Autonomous role for endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation.
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Tetrahydrobiopterin supplementation reduces atherosclerosis and vascular inflammation in apolipoprotein E-knockout mice.
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יצא לאור: (2010)

Endothelial cell tetrahydrobiopterin deficiency attenuates LPS-induced vascular dysfunction and hypotension
מאת: Chuaiphichai, S, et al.
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Low-dose Tetrahydrobiopterin Supplementation Reduces Atherosclerosis Progression in Apolipoprotein E-Knockout Mice via Effects on Vascular T cell Infiltration
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יצא לאור: (2009)

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Increased endothelial tetrahydrobiopterin reduces in stent stenosis in apolipoprotein E-knockout mice
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יצא לאור: (2007)

Increased Endothelial Tetrahydrobiopterin Reduces In Stent Stenosis in Apolipoprotein E-Knockout Mice
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Endothelial cell vasodilator dysfunction mediates progressive pregnancy-induced hypertension in endothelial cell tetrahydrobiopterin deficient mice.
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יצא לאור: (2023)

Endothelial GTP cyclohydrolase and tetrahydrobiopterin regulate gestational blood pressure, uteroplacental remodeling and fetal growth
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יצא לאור: (2021)

Deficiency in endothelial cell tetrahydrobiopterin increases resistance vascular remodelling, blood pressure, and susceptibility to aortic abdominal aneurysm in response to angiotensin II
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The requirement for endothelial cell tetrahydrobiopterin in health and disease
מאת: Chuaiphichai, S
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Tetrahydrobiopterin in cardiovascular health and disease.
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Increased endothelial tetrahydrobiopterin synthesis reduces vein graft atherosclerosis in ApoE-knockout mice
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יצא לאור: (2005)

Dihydrofolate reductase protects endothelial nitric oxide synthase from uncoupling in tetrahydrobiopterin deficiency.
מאת: Crabtree, M, et al.
יצא לאור: (2011)

Dihydrofolate reductase protects endothelial nitric oxide synthase from uncoupling in tetrahydrobiopterin deficiency
מאת: Crabtree, M, et al.
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Endothelial cell tetrahydrobiopterin modulates sensitivity to Ang (Angiotensin) II–induced vascular remodeling, blood pressure, and abdominal aortic aneurysm
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Synthesis and recycling of tetrahydrobiopterin in endothelial function and vascular disease.
מאת: Crabtree, M, et al.
יצא לאור: (2011)

Synthesis and recycling of tetrahydrobiopterin in endothelial function and vascular disease
מאת: Crabtree, M, et al.
יצא לאור: (2011)

Integrated redox sensor and effector functions for tetrahydrobiopterin- and glutathionylation-dependent endothelial nitric-oxide synthase uncoupling.
מאת: Crabtree, M, et al.
יצא לאור: (2013)

Regulation of endothelial nitric oxide synthase (eNOS) by tetrahydrobiopterin in vascular disease
מאת: Alp, N, et al.
יצא לאור: (2004)

Endothelial tetrahydrobiopterin (BH4) regulates eNOS coupling in vivo: Functional effects of BH4-eNOS stoichiometry in endothelial targeted transgenic mice
מאת: Bendall, J, et al.
יצא לאור: (2005)

Tetrahydrobiopterin- and glutathionylation-dependent regulation of eNOS coupling: Relationships revealed by eNOS glutathionylation mutants in cells with tet-regulated GTP cyclohydrolase I expression
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יצא לאור: (2012)

Endothelial nitric oxide synthase dysfunction in diabetic mice: importance of tetrahydrobiopterin in eNOS dimerisation.
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Increased endothelial tetrahydrobiopterin synthesis reduces vein graft accelerated atherosclerosis in apolipoprotein E-knockout mice
מאת: Ali, Z, et al.
יצא לאור: (2006)

Regulation of β-adrenergic control of heart rate by GTP-cyclohydrolase 1 (GCH1) and tetrahydrobiopterin.
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Regulation of endothelial nitric oxide synthase by tetrahydrobiopterin in vascular disease.
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The role of tetrahydrobiopterin in inflammation and cardiovascular disease.
מאת: McNeill, E, et al.
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Regulation of β-adrenergic control of heart rate by GTP-cyclohydrolase 1 (GCH1) and tetrahydrobiopterin
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Tetrahydrobiopterin-dependent eNOS coupling determines vascular remodeling through accelerated endothelial regeneration
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Increased endothelial tetrahydrobiopterin synthesis by targeted transgenic GTP-cyclohydrolase I overexpression reduces endothelial dysfunction and atherosclerosis in ApoE-knockout mice.
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יצא לאור: (2004)