DNA sequence specificity of triplex-binding ligands.

DNA sequence specificity of triplex-binding ligands.

We have examined the ability of naphthylquinoline, a 2,7-disubstituted anthraquinone and BePI, a benzo[e]pyridoindole derivative, to stabilize parallel DNA triplexes of different base composition. Fluorescence melting studies, with both inter- and intramolecular triplexes, show that all three ligand...

Descripció completa

Dades bibliogràfiques
Autors principals:	Keppler, MD, James, P, Neidle, S, Brown, T, Fox, K
Format:	Journal article
Idioma:	English
Publicat:	2003

Ítems similars

DNA triple helix stabilisation by covalent attachment of a triplex-specific ligand.
per: Keppler, MD, et al.
Publicat: (1999)

Formation of stable DNA triplexes.
per: Fox, K, et al.
Publicat: (2011)

5-(1-propargylamino)-2'-deoxyuridine (UP): a novel thymidine analogue for generating DNA triplexes with increased stability.
per: Bijapur, J, et al.
Publicat: (1999)

DNA triplex formation with 5-dimethylaminopropargyl deoxyuridine.
per: Rusling, D, et al.
Publicat: (2009)

The stability of triplex DNA is affected by the stability of the underlying duplex.
per: Rusling, D, et al.
Publicat: (2009)

Secondary binding sites for heavily modified triplex forming oligonucleotides.
per: Cardew, A, et al.
Publicat: (2012)

Crystal structure of a berenil-dodecanucleotide complex: the role of water in sequence-specific ligand binding.
per: Brown, D, et al.
Publicat: (1990)

Triplex-directed covalent cross-linking of a DNA nanostructure.
per: Rusling, D, et al.
Publicat: (2012)

Triplex staples: DNA double-strand cross-linking at internal and terminal sites using psoralen-containing triplex-forming oligonucleotides.
per: Li, H, et al.
Publicat: (2006)

Triplex-directed recognition of a DNA nanostructure assembled by crossover strand exchange.
per: Rusling, D, et al.
Publicat: (2012)

Sequence-specific DNA binding agents /
per: Waring, Michael J., et al.
Publicat: (2006)

Synthesis of anthraquinone oligonucleotides for triplex stabilization.
per: Zhao, Z, et al.
Publicat: (2007)

Triplex addressability as a basis for functional DNA nanostructures.
per: Tumpane, J, et al.
Publicat: (2007)

Synthesis of a novel bis-amino-modified thymidine monomer for use in DNA triplex stabilisation
per: Sollogoub, M, et al.
Publicat: (2000)

Stabilisation of self-assembled DNA crystals by triplex-directed photo-cross-linking
per: Abdallah, H, et al.
Publicat: (2016)

Secondary binding sites for triplex-forming oligonucleotides containing bulges, loops, and mismatches in the third strand.
per: Fox, K, et al.
Publicat: (2000)

Sequence-dependent drug binding to the minor groove of DNA: crystal structure of the DNA dodecamer d(CGCAAATTTGCG)2 complexed with propamidine
per: Nunn, Christine M., et al.
Publicat: (1995)

Oxidative DNA cleavage with clip‐phenanthroline triplex‐forming oligonucleotide hybrids
per: Panattoni, A, et al.
Publicat: (2019)

Solution conformation of an intramolecular DNA triplex containing a nonnucleotide linker: comparison with the DNA duplex.
per: Bartley, J, et al.
Publicat: (1997)

2 '-Substituted 2-amino-3-methylpyridine ribonucleosides in triplex-forming oligonucleotides: triplex stability is determined by chemical environment
per: Lou, C, et al.
Publicat: (2011)

DNA minor groove recognition of a non-self-complementary AT-rich sequence by a tris-benzimidazole ligand
per: Aymami, Juan, et al.
Publicat: (1999)

Towards the targeted modulation of gene expression by modified triplex-forming oligonucleotides
per: Rusling, D, et al.
Publicat: (2008)

Deep learning based DNA:RNA triplex forming potential prediction
per: Zhang, Yu, et al.
Publicat: (2021)

Solution conformation of a parallel DNA triple helix with 5' and 3' triplex-duplex junctions.
per: Asensio, J, et al.
Publicat: (1999)

Four base recognition by triplex-forming oligonucleotides at physiological pH.
per: Rusling, D, et al.
Publicat: (2005)

Potent triple helix stabilization by 5',3'-modified triplex-forming oligonucleotides.
per: Ben Gaied, N, et al.
Publicat: (2009)

Fluorogenic thiazole orange TOTFO probes stabilise parallel DNA triplexes at pH 7 and above
per: Walsh, S, et al.
Publicat: (2018)

Modeling pK shift in DNA triplexes containing locked nucleic acids
per: Hartono, Yossa Dwi, et al.
Publicat: (2019)

Selectivity and affinity of triplex-forming oligonucleotides containing 2'-aminoethoxy-5-(3-aminoprop-1-ynyl)uridine for recognizing AT base pairs in duplex DNA.
per: Osborne, S, et al.
Publicat: (2004)

Kinetic studies on the formation of DNA triplexes containing the nucleoside analogue 2'-O-(2-aminoethyl)-5-(3-amino-1-propynyl)uridine.
per: Rusling, D, et al.
Publicat: (2008)

Stable recognition of TA interruptions by triplex forming oligonucleotides containing a novel nucleoside.
per: Wang, Y, et al.
Publicat: (2005)

Tetrad-binding ligands do not bind specifically to left-handed G-quadruplexes
per: Das, Poulomi, et al.
Publicat: (2023)

The effect of sequence context on the activity of cytosine DNA glycosylases.
per: Kimber, S, et al.
Publicat: (2015)

2'-Aminoethoxy-2-amino-3-methylpyridine in triplex-forming oligonucleotides: high affinity, selectivity and resistance to enzymatic degradation.
per: Lou, C, et al.
Publicat: (2011)

2'-Aminoethoxy-2-amino-3-methylpyridine in triplex-forming oligonucleotides: high affinity, selectivity and resistance to enzymatic degradation.
per: Lou, C, et al.
Publicat: (2011)

Dynamic self-assembly of DNA minor groove-binding ligand DB921 into nanotubes triggered by an alkali halide
per: Mizuta, R, et al.
Publicat: (2018)

Sequence effects of single base loops in intramolecular quadruplex DNA.
per: Rachwal, P, et al.
Publicat: (2007)

Advances in DNA sequence specific agents /
per: Hurley, Laurence H.
Publicat: (1992)

DNA sequence recognition by an isopropyl substituted thiazole polyamide.
per: James, P, et al.
Publicat: (2004)

High throughput measurement of duplex, triplex and quadruplex melting curves using molecular beacons and a LightCycler.
per: Darby, R, et al.
Publicat: (2002)