Dissection of the multiple sclerosis associated DR2 haplotype.

Epidemiological and genetic data have consistently identified associations with HLA class II alleles in many autoimmune diseases. In multiple sclerosis (MS), an autoimmune disease targeting central nervous system (CNS) myelin, the DR2 haplotype (DRB1*1501, DRB5*0101 and DQB1*0602) remains the strong...

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Autors principals: Etzensperger, R, McMahon, R, Jones, E, Fugger, L
Format: Journal article
Idioma:English
Publicat: 2008