Ataxin-3 links NOD2 and TLR2 mediated innate immune sensing and metabolism in myeloid cells
The interplay between NOD2 and TLR2 following recognition of components of the bacterial cell wall peptidoglycan is well-established, however their role in redirecting metabolic pathways in myeloid cells to degrade pathogens and mount antigen presentation remains unclear. We show NOD2 and TLR2 media...
Main Authors: | Chapman, T, Corridoni, D, Shiraishi, S, Pandey, S, Aulicino, A, Wigfield, S, Do Carmo Costo, M, Thezenas, M, Paulson, H, Fischer, R, Kessler, B, Simmons, A |
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Format: | Journal article |
Published: |
Frontiers Media
2019
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